Classes > 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide
Page last updated: 2024-08-05 12:42:36
4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide
A benzocycloheptapyridine that is benzo[5,6]cyclohepta[1,2-b]pyridine which is substituted at positions 3 and 10 by bromines, at position 8 by chlorine, and at position 11 by an N-acetylpiperidin-4-yl group in which one of the hydrogens of the acetyl moiety has been replaced by a 1-carbamoylpiperidin-4-yl group.
ChEBI ID: 90678
Members (1)
| Member | Definition | Role |
|---|
| lonafarnib | A 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide that has R configuration. It is used as oral farnesyltransferase inhibitor. | lonafarnib |
Research
Studies (220)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (4.55) | 18.2507 |
| 2000's | 117 (53.18) | 29.6817 |
| 2010's | 62 (28.18) | 24.3611 |
| 2020's | 31 (14.09) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 34 (15.18%) | 5.53% |
| Reviews | 52 (23.21%) | 6.00% |
| Case Studies | 2 (0.89%) | 4.05% |
| Observational | 1 (0.45%) | 0.25% |
| Other | 135 (60.27%) | 84.16% |